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Prices are from Yahoo! Finance and may be delayed. Always check the latest price before trading.
IONIS PHARMACEUTICALS INC closed at $39.42 on Nov 6, 2026, −10.4% over 1 month, −46.4% over 1 year.
If you had invested $1,000 1 month ago, it would be worth $896 today (−10.4%).Price change only; dividends and fees are not included.
Over the same period the S&P 500 moved −5.7%, while this stock moved −10.4%.
| Date | Close | Change | % Change |
|---|---|---|---|
| Nov 6 (Fri) | $39.42 | +0.62 | +1.60% |
| Nov 5 (Thu) | $38.80 | −1.35 | −3.36% |
| Nov 4 (Wed) | $40.15 | −0.27 | −0.67% |
| Nov 3 (Tue) | $40.42 | −0.82 | −1.99% |
| Nov 2 (Mon) | $41.24 | −2.28 | −5.24% |
| Oct 30 (Fri) | $43.52 | −0.87 | −1.96% |
| Oct 29 (Thu) | $44.39 | −0.51 | −1.14% |
| Oct 28 (Wed) | $44.90 | +0.94 | +2.14% |
| Oct 27 (Tue) | $43.96 | +0.54 | +1.24% |
| Oct 26 (Mon) | $43.42 | +0.49 | +1.14% |
If you had invested $1,000 3 months ago, it would be worth $723 today (−27.7%).Price change only; dividends and fees are not included.
Over the same period the S&P 500 moved −4.3%, while this stock moved −27.7%.
| Date | Close | Change | % Change |
|---|---|---|---|
| Nov 6 (Fri) | $39.42 | +0.62 | +1.60% |
| Nov 5 (Thu) | $38.80 | −1.35 | −3.36% |
| Nov 4 (Wed) | $40.15 | −0.27 | −0.67% |
| Nov 3 (Tue) | $40.42 | −0.82 | −1.99% |
| Nov 2 (Mon) | $41.24 | −2.28 | −5.24% |
| Oct 30 (Fri) | $43.52 | −0.87 | −1.96% |
| Oct 29 (Thu) | $44.39 | −0.51 | −1.14% |
| Oct 28 (Wed) | $44.90 | +0.94 | +2.14% |
| Oct 27 (Tue) | $43.96 | +0.54 | +1.24% |
| Oct 26 (Mon) | $43.42 | +0.49 | +1.14% |
If you had invested $1,000 6 months ago, it would be worth $513 today (−48.7%).Price change only; dividends and fees are not included.
Over the same period the S&P 500 moved +0.2%, while this stock moved −48.7%.
| Month | Month-End Close | Monthly % |
|---|---|---|
| Nov 2026 | $39.42 | −9.4% |
| Oct 2026 | $43.52 | −2.5% |
| Sep 2026 | $44.65 | −26.0% |
| Aug 2026 | $60.36 | +16.6% |
| Jul 2026 | $51.77 | −34.7% |
| Jun 2026 | $79.29 | +3.6% |
| May 2026 | $76.50 | +2.3% |
If you had invested $1,000 1 year ago, it would be worth $536 today (−46.4%).Price change only; dividends and fees are not included.
Over the same period the S&P 500 moved +9.6%, while this stock moved −46.4%.
| Month | Month-End Close | Monthly % |
|---|---|---|
| Nov 2026 | $39.42 | −9.4% |
| Oct 2026 | $43.52 | −2.5% |
| Sep 2026 | $44.65 | −26.0% |
| Aug 2026 | $60.36 | +16.6% |
| Jul 2026 | $51.77 | −34.7% |
| Jun 2026 | $79.29 | +3.6% |
| May 2026 | $76.50 | +2.3% |
| Apr 2026 | $74.76 | −0.4% |
| Mar 2026 | $75.09 | −7.5% |
| Feb 2026 | $81.15 | −1.8% |
| Jan 2026 | $82.67 | +4.5% |
| Dec 2025 | $79.11 | −4.4% |
| Nov 2025 | $82.73 | ― |
If you had invested $1,000 3 years ago, it would be worth $850 today (−15.0%).Price change only; dividends and fees are not included.
Over the same period the S&P 500 moved +67.1%, while this stock moved −15.0%.
| Year | Year-End Close | Yearly % |
|---|---|---|
| 2026 (YTD) | $39.42 | −50.2% |
| 2025 | $79.11 | ― |
If you had invested $1,000 5 years ago, it would be worth $1,206 today (+20.6%).Price change only; dividends and fees are not included.
Over the same period the S&P 500 moved +57.5%, while this stock moved +20.6%.
| Year | Year-End Close | Yearly % |
|---|---|---|
| 2026 (YTD) | $39.42 | −50.2% |
| 2025 | $79.11 | ― |
If you had invested $1,000 in Jun 1991, it would be worth $3,846 today (+284.6%).Price change only; dividends and fees are not included.
Over the same period the S&P 500 moved +1,765.5%, while this stock moved +284.6%.
| Year | Year-End Close | Yearly % |
|---|---|---|
| 2026 (YTD) | $39.42 | −50.2% |
| 2025 | $79.11 | +126.3% |
| 2024 | $34.96 | −30.9% |
| 2023 | $50.59 | +33.9% |
| 2022 | $37.77 | +24.1% |
| 2021 | $30.43 | −46.2% |
| 2020 | $56.54 | −6.4% |
| 2019 | $60.41 | +11.7% |
| 2018 | $54.06 | +7.5% |
| 2017 | $50.30 | +5.2% |
| 2016 | $47.83 | −22.8% |
| 2015 | $61.93 | +0.3% |
| 2014 | $61.74 | +55.0% |
| 2013 | $39.84 | +281.6% |
| 2012 | $10.44 | +44.8% |
| 2011 | $7.21 | −28.8% |
| 2010 | $10.12 | −8.9% |
| 2009 | $11.11 | −21.7% |
| 2008 | $14.18 | −10.0% |
| 2007 | $15.75 | +41.6% |
| 2006 | $11.12 | +112.2% |
| 2005 | $5.24 | −11.2% |
| 2004 | $5.90 | −9.2% |
| 2003 | $6.50 | −1.4% |
| 2002 | $6.59 | −70.3% |
| 2001 | $22.19 | +108.8% |
| 2000 | $10.63 | +70.0% |
| 1999 | $6.25 | −51.7% |
| 1998 | $12.94 | +5.1% |
| 1997 | $12.31 | −31.6% |
| 1996 | $18.00 | +37.1% |
| 1995 | $13.13 | +228.1% |
| 1994 | $4.00 | −40.7% |
| 1993 | $6.75 | −30.8% |
| 1992 | $9.75 | −29.1% |
| 1991 | $13.75 | ― |
Daily, weekly and monthly closes (Yahoo! Finance, split-adjusted, dividends excluded). "All" covers the range Yahoo provides (from Jun 1991). Please check the latest prices before trading.
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